IT & Systems Jobs in San Francisco
95 open it & systems jobs in San Francisco, CA, as of Nov 10, 2026. Of the 50 newest, 13 are remote or hybrid and 16 list a salary. Hiring most: Cogent Security, Anthropic and Cognition. Every listing comes from the employer’s own hiring system.
Plus 257 remote it & systems jobs open to people anywhere in the US.
Astro Mechanica
San Francisco, California · On-site · US$140,000–170,000 / year
The San Francisco Compute Company
San Francisco, California · On-site · US$250,000–325,000 / year
Rad AI
San Francisco, California · Remote · US$86,000–115,000 / year
Happyrobot Inc.
San Francisco, California · Hybrid · US$120,000–160,000 / year
Zyphra
San Francisco, California · On-site
Crypto.com
San Francisco, California · Hybrid · US$130,000–150,000 / year
Abby Care
San Francisco, California · Hybrid · US$120,000–155,000 / year
Lucidcomputing
San Francisco, California · Hybrid · US$100,000–450,000 / year
No job selected
Astro Mechanica
San Francisco, California · On-site · US$140,000–170,000 / year
The San Francisco Compute Company
San Francisco, California · On-site · US$250,000–325,000 / year
Rad AI
San Francisco, California · Remote · US$86,000–115,000 / year
Happyrobot Inc.
San Francisco, California · Hybrid · US$120,000–160,000 / year
Zyphra
San Francisco, California · On-site
Crypto.com
San Francisco, California · Hybrid · US$130,000–150,000 / year
Abby Care
San Francisco, California · Hybrid · US$120,000–155,000 / year
Lucidcomputing
San Francisco, California · Hybrid · US$100,000–450,000 / year
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